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Image Search Results
Journal: JCI Insight
Article Title: SARS-CoV-2–specific immune responses in boosted vaccine recipients with breakthrough infections during the Omicron variant surge
doi: 10.1172/jci.insight.159474
Figure Lengend Snippet: IFN-γ ELIspot assay was performed with overlapping spike peptide pools from ( A ) vaccine strain and ( B ) S1 spike proteins from vaccine strain or Omicron variant in VR21, VR26, and VR37 1–3 weeks after boost in A; in VR37 and VR97 1–3 weeks after boost in B; and in breakthrough VRs. IFN-γ spot-forming units (SFU) per million PBMCs are shown. Orange diamonds represent VR21, VR26, VR37, and VR97 at the breakthrough time point. Statistical comparisons were done using ordinary 1-way ANOVA (unpaired) and Holm-Šidák’s multiple comparison test, with a single pool variance used. * P =0.0332, ** P =0.0021.
Article Snippet: The IFN-γ ELISpot assay was used to analyze T cell responses to SARS-CoV-2 spike and nucleocapsid peptide pools (BEI Resources) and the
Techniques: Enzyme-linked Immunospot, Variant Assay, Comparison